2001-2002
Undergraduate Calendar Programs| 2001-2002
Undergraduate Calendar Programs |
||
| 2001-2002 UNDERGRADUATE CALENDAR | ||
| Carleton University |
2240 Herzberg Building
Telephone: 520-3515
Fax: 520-2569
Academic Administration
Director
P. Buist
Members of the Institute
• P. Buist • N. Chaly • J.J. Cheetham • B. Hollebone • I.B. Lambert • J. Sinclair• M.L. Smith • K.B. Storey • J. Vierula • D.C. Wigfield • R.C. Wyndham
Associate Member
V.L. Seligy
Teaching Staff
Professor
K.B. Storey, B.Sc. (Calgary), Ph.D. (British Columbia), F.R.S.C.
Associate Professors
J.J. Cheetham, B.Sc., Ph.D. (McMaster) • Iain B. Lambert, B.Sc. (Guelph), Ph.D. (McMaster) • J. Sinclair, B.Sc., Dip.in Biophysics (Edinburgh), Ph.D. (East Anglia)
Adjunct Research Professors
J. David Miller • H. Yamazaki
Adjunct Professor
Chishium S. Tsai
Graduation Regulations
In order to graduate, students must fulfill all University graduation Regulations and all Faculty regulations, in addition to all regulations and requirements of the Institute as set out below.
Honours Programs
Honours Bachelor of Science in Biochemistry and Biotechnology
See description of this special program.
Honours Bachelor of Science in Biochemistry
The Institute of Biochemistry also offers a four-year program leading to an Honours B.Sc. in Biochemistry, intended to provide more specialized training for biochemical research or a related career. An Honours degree with above-average standing is normally required for post-graduate studies in this discipline.
Students entering the program must satisfy the general requirements for B.Sc. Honours . The following 20.0 credits are required, taken in a pattern approved by the Director of the Institute:
1. Biology 61.103*, 61.214*, 61.314*, either 61.201* or 61.202*, either 61.325* or 61.335*, and 1.0 credit selected from approved 300- or 400-level Biology courses (see Note 6);
2. Chemistry 65.100, 65.210 or 65.211* and 65.353*, 65.220 or 65.223*, and 65.224*, 65.233*, 65.321*, 65.322*, 65.325*;
3. (a) Biochemistry 63.220*, 63.305*, 63.310, 63.401*, and 63.497 or 63.498;
(b) At least 1.0 credit chosen from: Biochemistry 63.402*, 63.404*, 63.405*, 63.406*, 63.407*, 63.422*, 63.432, 63.440*;
4. Physics 75.107* and 75.108*, Mathematics 69.107*, 69.117*, and 69.257*;
5. 0.5 credits in Natural Sciences 66.100* or an arts or social sciences elective.
6. 1.5 credits in approved arts or social sciences electives
7. 1.5 credits related to the student's area of specialization. Some recommended courses include: Biochemistry courses listed in 3(b) above, 63.491*; Biology courses listed in note 6 below; Chemistry 65.212*, 65.311*, 65.312*, 65.353*, 65.354*, 65.370*, 65.380*, 65.422*, 65.423*; Physics 75.235*, 75.236*; Mathematics 69.207*, 69.208*, 69.217*; Computer Science 95.102*;
8. 1.0 free option credit or 0.5 free option credit if Biology 61.102 is taken in lieu of the Ontario Academic Credit in Biology.
Notes on Programs:
1. A completed credit for Biology 61.102 or 61.209* and 61.230* may replace the requirement for Biology 61.103* and 61.104*. Students who have completed only Biology 61.230* may replace 61.103*and 61.104* with 61.230* plus a 0.5 credit Biology elective. Students who have completed only 61.209* must sucessfully complete 61.103* and 61.104*; Biology 61.209* may then be credited as a free elective.
2. For the purposes of calculation, the Major or Honours subjects include all Biochemistry courses, plus the Biology and Chemistry courses fulfilling requirements 1 and 2 in each program.
3. In choosing a program, students should consider the prerequisites required for any courses that they wish to take in later years. In particular, some options may be offered only in alternate years and may require as prerequisites one or other of Biology 61.325*, 61.233* and 61.335*. Because of timetable constraints, students may have to take Chemistry 65.210 and Biology 61.201* or 61.202* in different years.
4. Credit will not be given for Biology 61.220* or Biochemistry 63.220* taken after Biochemistry 63.310 or equivalent.
5. "Permission of the Institute" in course prerequisites normally means permission of the Director or the Honours Project co-ordinator.
6. The following 300-400 level Biology courses are approved to satisfy requirement 1 for Biochemistry students: 61.321*, 61.325*, 61.331*, 61.333*, 61.335*, 61.351*, 61.355*, 61.408*, 61.409*, 61.413*, 61.414*, 61.416*, 61.419*, 61.421*, 61.426*, 61.429*, 61.430*, 61.431*, 61.432*, 61.433*, 61.435 and 61.455.
7. To qualify for graduation with a Major in Biochemistry students must meet the requirements on p. 150 except that they must present 20.0 approved full credits beyond Qualifying-University year and have a grade of C- or better in at least half of the 20.0 credits.
8. Students who wish to take 61.214* in the Winter term of their first year must obtain a grade of C- or better in 61.103*.
A typical First Year course pattern in a Biochemistry program will be the same as that for Biochemistry and Biotechnology.
Co-op Option for Honours Biochemistry
General information on the Co-op option can be found in the Co-operative Education section.
Co-operative education formally integrates a student's academic experience with working in industry and/or government. Work opportunities, which are available on a competitive basis, are co-ordinated to complement a student's course work and interests. Practical work experience provides insights and opportunities for development, and helps prepare an individual for a career in Biochemistry.
Operation of the Co-operative Option
The program is administered by the Co-operative Program Committee which is responsible for securing potential employers, arranging interviews, and managing the program. The details of the program are provided in the Biochemistry Co-op Student Handbook.
Admission Requirements
Students in good standing in the Honours Biochemistry Program may apply for admission to the B.Sc.(Honours) Co-operative option on completion of their first, second or third years. To be eligible for admission, a student must:
1. be registered as a full-time student;
2. have a GPA in Biochemistry of 8.0 or better and an overall GPA of 6.5 or better;
3. be eligible to work in Canada.
A student meeting these requirements is eligible for the Co-op Program but enrollment in the program is limited. Application forms for admission to the Co-operative option are available from the Co-op Office. These forms should be completed and returned to the office before November 1, March 1, July 1, for May, September, January work terms respectively.
The Work/Study Sequence
There are normally three (four month) work terms, but an additional work term will be permitted in exceptional circumstances, e.g. where employment conditions require it. Work terms can occur during the summer after second and third years and during fourth year. Students must have successfully completed 63.220* or 61.220* as well as 65.223* before they can begin their first work term.
Continuation in the Program
To continue in the Co-op option, students must maintain a GPA in Biochemistry of 8.0 or better, and an overall GPA of 6.5 or better.
During work terms, students must be registered in 63.299*, 63.399* or 63.499* . Successful completion of a work term requires that the student hand in a Work Term Report which is reviewed by the Co-operative program committee and found to merit a "Satisfactory" grade. The requirements for the report and the evaluation criteria are described in the Biochemistry Co-op Student Handbook, which also lists circumstances in which a student may be required to withdraw from the Co-op option. Students must also maintain the Co-op Option academic requirements mentioned above.Graduation Requirements
Students must complete the 20.0 credits specified for the Biochemistry Honours program, as well as the three work term credits with the appropriate level of grades. Successful completion of these requirements will lead to the award of an Honours degree in Biochemistry with the Co-operative degree designation.
Honours Bachelor of Science in Computational Biochemistry
This program is intended for students who enjoy the challenges of both Biochemistry and Computer Science. e.g. students who wish to enter the field of bioinformatics.
1. 2.5 credits in Biology: 61.103*, 61.214*, 61.314* and another 1.0 credit at the 100-level or higher;
2. 3.5 credits in Chemistry : 65.100, 65.223*, 65.224* or 65.226*, 65.211*, 65.233*, 65.353*;
3. 2.5 credits in Biochemistry : 63.220*, 63.305*, 63.310, 63.406*
4. 1.0 credit in Biochemistry at the 400-level or Chemistry 65.446* and 0.5 credit in Biochemistry at the 400-level;
5. 1.0 credit in Physics: 75.107* and 75.108*; or 75.103* and 75.104*
6. 1.5 credits in Mathematics: 69.107*, 69.117*, and 69.257*;
7. 2.0 credits in Computer Science 95.105*, 95.106*, 95.202 and an additional 0.5 credits in Computer Science at the 200 level or above;
8. 2.5 credits in Computational Science: 68.280*, 68.499 and an additional 1.0 credits in Computational Science;
9. 2.0 credits in approved arts or social sciences electives
10. 1.5 free option credit.
Notes on programs:
1. The 4.0 credits in Computer Science must be completed with a cumulative GPA of 6.5 or better.
2. The GPA in Biochemistry is calculated on the basis of all Biochemistry courses plus the Biology and Chemistry courses in 1 and 2 above.
Major Program
Bachelor of Science in Biochemistry
The Institute of Biochemistry offers a four-year (20.0 credit) programleading to a B.Sc. majoring in Biochemistry and intended to provide a broad basic training for students who have a general interest in biological functions at the molecular level or who are planning a career in biochemistry or a related field of biomedical science that does not demand post-graduate study. Courses in Biology and Chemistry (and resources from these departments) are integrated into the program to provide the background that is fundamental to an understanding of the biochemistry of animals, microorganisms and plants.
Many graduates from the 15-credit B.Sc. programs in Biology or Chemistry may qualify for admission to the final year of the Major B.Sc. in Biochemistry, if they have successfully completed the 300-level Biochemistry courses. Students entering the program must satisfy the general requirements for a Major B.Sc. The following 20.0 credits are required:
1. 3.5 Biology credits: 61.103*, 61.214*, 61.314*, either 61.201* or 61.202*, either 61.325* or 61.335*, and 1.0 credit selected from approved 300- or 400-level Biology courses (see Note 6);
2. 4.5 Chemistry credits: 65.100, 65.210 or 65.211* and 65.353*, 65.220 or 65.223* and 65.224*, 65.233*, 65.321*, 65.322* or 65.325*.
3. (a) Biochemistry 63.220*, 63.305*, 63.310, 63.401*, and
(b) at least 1.0 credit chosen from: Biochemistry 63.402*, 63.404*, 63.405*, 63.406*, 63.407*, 63.422*, 63.432*;
4. Physics 75.107* and 75.108*, Mathematics 69.107*, 69.117* and 69.257*;
5. 0.5 credits in Natural Sciences 66.100* or an arts or social sciences elective.
6. 1.5 credits in approved arts or social sciences electives
7. 3.0 credits related to the student's area of interest. Some recommended courses include: Biochemistry listed in 3(b) above, 63.491*; Biology courses listed in note 6 above; Chemistry 65.212*, 65.311*, 65.312*, 65.322*, 65.325*, 65.353*, 65.354*, 65.370*, 65.380*, 65.422*, 65.423*; Physics 75.235*, 75.236*; Mathematics 69.207*, 69.208*, 69.217*, 69.257*; Computer Science 95.107*;
8. 1.0 credit free option.
Graduate Program
No graduate program is offered by the Institute but the graduate offerings of the Departments of Biology and Chemistry include projects and courses that may be appropriate for students with an interest in biochemistry. Details are found in the Graduate Studies and Research Calendar.
Courses
Not all of the following courses are offered in a given year. For an up-to-date statement of course offerings for 2001-2002, please consult the Registration Instructions and Class Schedule booklet published in the summer.
Natural Sciences 66.100*
Seminar in Science
This cross-disciplinary course presents a survey of current issues in science. The course provides new science students with an orientation to the study of science at the university level. The course is structured around seminars, oral and written presentations.
Restricted to students in the first year of B.Sc. programs or BA Biology programs.
Lectures and tutorials three hours per week
Biochemistry 63.220*
Cell Physiology and Biochemistry
A lecture and laboratory course on cellular functions and their inter-relationships. It introduces topics including thermodynamics, membrane structure and function, transport mechanisms, basic metabolic pathways, energy production and utilization, communications between cells. (Also listed as Biology 61.220*.)
Precludes additional credit for Biology 61.220*. Credit will not normally be given for Biochemistry 63.220* or equivalent taken after Biochemistry 63.310.
Prerequisites: Biology 61.103* and or equivalent, Chemistry 65.100 or permission of the Institute.
Lectures three hours a week, laboratory four hours a week.
Biochemistry 63.299*
Co-operative Work Term Report 1
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites : Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.
Biochemistry 63.305*
Practical Biochemistry
A laboratory and tutorial course introducing the basics of experimental biochemistry and illustrating the theory and concepts dealt with in Biochemistry 63.310.
Prerequisites: Chemistry 65.220 or 65.223* and 65.224*; Chemistry 65.210 or 65.211* or Biochemistry 63.220*/Biology 61.220* with a grade of C- or better, or permission of the Institute. Biochemistry 63.310 or equivalent is recommended as a co-requisite.
Laboratory four hours a week plus biweekly assignments.
Biochemistry 63.310
General Biochemistry
Chemistry and metabolism of proteins, lipids, carbohydrates and nucleic acids. Mechanism of action of enzymes. Metabolic control mechanisms and inter-relations. Biological oxidation. Biosynthesis of structural, storage and informational compounds.
Prerequisites: Chemistry 65.220 or 65.223* and 65.224*; Chemistry 65.210 or 65.211* or Biochemistry 63.220*/Biology 61.220* with a grade of C- or better, or permission of the Institute. A course in genetics is strongly recommended.
Lectures three hours a week.
Biochemistry 63.399*
Co-operative Work Term Report 2
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites: Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.
Biochemistry 63.401*
Methods in Biochemistry
The course deals with the principles and applications of modern biochemical methodology, including use of radioisotope tracers, ultracentrifugation, electrophoresis and ion-exchange chromatography.
Prerequisite: Biochemistry 63.305* or permission of the Institute.
Lectures and discussion two hours, laboratory six hours a week.
Biochemistry 63.402*
Biomacromolecules
Biochemistry of polysaccharides, proteins and nucleic acids. Discussion of experimental approaches to purification and conformational studies of biomacromolecules, their interaction in solutions, function and regulation of enzymes. Workshop sessions include discussion of experimental design and interpretation, and solving of related numerical problems.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures two hours, workshop two hours a week.
Biochemistry 63.404*
Industrial Biochemistry
A course illustrating the application of biochemistry to the production of biological compounds useful in nutrition, medicine, and the food and chemical industries. The course also reviews the general strategies for efficient production of these compounds by controlling the activities of living cells or enzymes.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures three hours a week.
Biochemistry 63.405*
Biochemical Regulation
A half-credit in biochemical regulation. Topics include regulation at the transcriptional, translational and metabolic level. Regulation of cell and subcellular organelle function and other timely topics may also be included. A detailed course outline is available from the instructor in any given year.
Precludes additional credit for Biochemistry 63.403*.
Prerequisite: Biochemistry 63.310.
Lectures three hours a week.
Biochemistry 63.406*
Bioinformatics
The use of computers to solve biochemical problems. Topics may include data and software acquisition, sequence analyses, genomics, biomolecular interaction and kinetics, metabolic simulation, molecular modelling of biomolecules and biodiversity.
Prerequisites: Biochemistry 63.310; or permission of the Institute.
Lecture one hour a week, computer workshop three hours a week.
Biochemistry 63.407*
Membrane Biochemistry
Biochemical and biophysical aspects of biomembrane structure and function. Topics may include: membrane lipids and proteins, lipid polymorphism, model membranes, liposomes, membrane biogenesis, the membrane cytoskeleton, membrane trafficking, membrane fusion, exocytosis and signal transduction across membranes.
Prerequisite: Biology 61.220* or Biochemistry 63.220* or 63.310 (taken concurrently); or permission of the Institute.
Lectures two hours a week and workshop two hours a week.
Biochemistry 63.422*
Mutagenesis and DNA Repair
A mechanistic study of mutagenesis and DNA repair. Topics will include DNA structure perturbations, spontaneous and induced mutagenesis, the genetics and biochemistry of DNA repair and recombination, and the role of mutations in the development of genetic disease and cancer. (Also listed as Biology 61.422*).
Prerequisites: Biology 61.220* or Biochemistry 63.220* or 63.310 (taken concurrently); Biology 61.314*, or permission of the Institute.
Lectures two hours a week and workshop two hours a week.
Biochemistry 63.432*
Immunology
The organization and function of the immune system. The anatomy of the immune system, and the molecular and genetic bases of the immune response. The laboratory teaches applications of animal cell culture in studies of immune cells and their products. (Also listed as Biology 61.432*.)
Prerequisite: Biology 61.221* or 61.321*; or permission of the Institute.
Lectures three hours a week, laboratories four hours a week.
Biochemistry 63.440*
The Cell Cycle
A course on the molecular cell biology of the eukaryotic cell cycle. Topics will include regulation of cell proliferation and cell death, and the molecular basis for morphological remodelling during cell division and death. (Also listed as Biology 61.440*)
Prerequisites: Biology 61.321*, or Biochemistry 63.220* and Biochemistry 63.310.
Biochemistry 63.478*
Principles of Toxicology
This course identifies the basic theorems of toxicology with examples of current research problems. Toxic risk is defined as the product of intensive hazard and extensive exposure. Each factor is assessed in scientific and social contexts and illustrated with many types of experimental material. Also offered at the graduate level, with additional or different requirements, as Biology 61.642 and Chemistry 65.578, for which additional credit is precluded.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures three hours a week.
Biochemistry 63.491*
Selected Topics in Biochemistry
Selected topics of current interest in biochemistry are offered upon approval by the Director in consultation with members of the Institute.
Biochemistry 63.497
Honours Essay and Research Proposal
An independent research study using library resources. The candidate will prepare a critical review of a topic approved by a faculty advisor. Evaluation will be based on a report and an oral defence of the report.
Precludes additional credit for Biochemistry 63.498.
Prerequisite: Fourth-year standing in an Honours Biochemistry program and permission of the Institute.
Biochemistry 63.498
Research Project
Students carry out a research project approved by the Director, under the supervision of a faculty member of the Institute, in either the Biology or Chemistry departments. A report must be submitted to the supervisor by the last day of classes, and will be examined by committee.
Precludes additional credit for Biochemistry 63.497.
Prerequisites: Biochemistry 63.305* and 63.310 or equivalent, and eligibility to continue in Honours Biochemistry or in Biochemistry and Biotechnology.
Lectures and associated work average at least eight hours a week.
Biochemistry 63.499*
Co-operative Work Term Report 3
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites: Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.
Carleton
University
2001-2002 Undergraduate Calendar
1125 Colonel By Drive, Ottawa, ON, Canada K1S 5B6
General enquiries: (613) 520-7400
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