2001-2002 Undergraduate Calendar
	2001-2002 UNDERGRADUATE CALENDAR: COURSES
	Carleton University

Biochemistry Courses
Not all of the following courses are offered in a given year. For an up-to-date statement of course offerings for 2001-2002, please consult the Registration Instructions and Class Schedule booklet published in the summer.

Natural Sciences 66.100*
Seminar in Science
This cross-disciplinary course presents a survey of current issues in science. The course provides new science students with an orientation to the study of science at the university level. The course is structured around seminars, oral and written presentations.
Restricted to students in the first year of B.Sc. programs or BA Biology programs.
Lectures and tutorials three hours per week.

Biochemistry 63.220*
Cell Physiology and Biochemistry
A lecture and laboratory course on cellular functions and their inter-relationships. It introduces topics including thermodynamics, membrane structure and function, transport mechanisms, basic metabolic pathways, energy production and utilization, communications between cells. (Also listed as Biology 61.220*.)
Precludes additional credit for Biology 61.220*. Credit will not normally be given for Biochemistry 63.220* or equivalent taken after Biochemistry 63.310.
Prerequisites: Biology 61.103* and or equivalent, Chemistry 65.100 or permission of the Institute.
Lectures three hours a week, laboratory four hours a week.

Biochemistry 63.299*
Co-operative Work Term Report 1
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites : Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.

Biochemistry 63.305*
Practical Biochemistry
A laboratory and tutorial course introducing the basics of experimental biochemistry and illustrating the theory and concepts dealt with in Biochemistry 63.310.
Prerequisites: Chemistry 65.220 or 65.223* and 65.224*; Chemistry 65.210 or 65.211* or Biochemistry 63.220*/Biology 61.220* with a grade of C- or better, or permission of the Institute. Biochemistry 63.310 or equivalent is recommended as a co-requisite.
Laboratory four hours a week plus biweekly assignments.

Biochemistry 63.310
General Biochemistry
Chemistry and metabolism of proteins, lipids, carbohydrates and nucleic acids. Mechanism of action of enzymes. Metabolic control mechanisms and inter-relations. Biological oxidation. Biosynthesis of structural, storage and informational compounds.
Prerequisites: Chemistry 65.220 or 65.223* and 65.224*; Chemistry 65.210 or 65.211* or Biochemistry 63.220*/Biology 61.220* with a grade of C- or better, or permission of the Institute. A course in genetics is strongly recommended.
Lectures three hours a week.

Biochemistry 63.399*
Co-operative Work Term Report 2
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites: Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.

Biochemistry 63.401*
Methods in Biochemistry
The course deals with the principles and applications of modern biochemical methodology, including use of radioisotope tracers, ultracentrifugation, electrophoresis and ion-exchange chromatography.
Prerequisite: Biochemistry 63.305* or permission of the Institute.
Lectures and discussion two hours, laboratory six hours a week.

Biochemistry 63.402*
Biomacromolecules
Biochemistry of polysaccharides, proteins and nucleic acids. Discussion of experimental approaches to purification and conformational studies of biomacromolecules, their interaction in solutions, function and regulation of enzymes. Workshop sessions include discussion of experimental design and interpretation, and solving of related numerical problems.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures two hours, workshop two hours a week.

Biochemistry 63.404*
Industrial Biochemistry
A course illustrating the application of biochemistry to the production of biological compounds useful in nutrition, medicine, and the food and chemical industries. The course also reviews the general strategies for efficient production of these compounds by controlling the activities of living cells or enzymes.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures three hours a week.

Biochemistry 63.405*
Biochemical Regulation
A half-credit in biochemical regulation. Topics include regulation at the transcriptional, translational and metabolic level. Regulation of cell and subcellular organelle function and other timely topics may also be included. A detailed course outline is available from the instructor in any given year.
Precludes additional credit for Biochemistry 63.403*.
Prerequisite: Biochemistry 63.310.
Lectures three hours a week.

Biochemistry 63.406*
Bioinformatics
The use of computers to solve biochemical problems. Topics may include data and software acquisition, sequence analyses, genomics, biomolecular interaction and kinetics, metabolic simulation, molecular modelling of biomolecules and biodiversity.
Prerequisites: Biochemistry 63.310; or permission of the Institute.
Lecture one hour a week, computer workshop three hours a week.

Biochemistry 63.407*
Membrane Biochemistry
Biochemical and biophysical aspects of biomembrane structure and function. Topics may include: membrane lipids and proteins, lipid polymorphism, model membranes, liposomes, membrane biogenesis, the membrane cytoskeleton, membrane trafficking, membrane fusion, exocytosis and signal transduction across membranes.
Prerequisite: Biology 61.220* or Biochemistry 63.220* or 63.310 (taken concurrently); or permission of the Institute.
Lectures two hours a week and workshop two hours a week.

Biochemistry 63.422*
Mutagenesis and DNA Repair
A mechanistic study of mutagenesis and DNA repair. Topics will include DNA structure perturbations, spontaneous and induced mutagenesis, the genetics and biochemistry of DNA repair and recombination, and the role of mutations in the development of genetic disease and cancer. (Also listed as Biology 61.422*).
Prerequisites: Biology 61.220* or Biochemistry 63.220* or 63.310 (taken concurrently); Biology 61.314*, or permission of the Institute.
Lectures two hours a week and workshop two hours a week.

Biochemistry 63.432*
Immunology
The organization and function of the immune system. The anatomy of the immune system, and the molecular and genetic bases of the immune response. The laboratory teaches applications of animal cell culture in studies of immune cells and their products. (Also listed as Biology 61.432*.)
Prerequisite: Biology 61.221* or 61.321*; or permission of the Institute.
Lectures three hours a week, laboratories four hours a week.

Biochemistry 63.440*
The Cell Cycle
A course on the molecular cell biology of the eukaryotic cell cycle. Topics will include regulation of cell proliferation and cell death, and the molecular basis for morphological remodelling during cell division and death. (Also listed as Biology 61.440*)
Prerequisites: Biology 61.321*, or Biochemistry 63.220* and Biochemistry 63.310.

Biochemistry 63.478*
Principles of Toxicology
This course identifies the basic theorems of toxicology with examples of current research problems. Toxic risk is defined as the product of intensive hazard and extensive exposure. Each factor is assessed in scientific and social contexts and illustrated with many types of experimental material. Also offered at the graduate level, with additional or different requirements, as Biology 61.642 and Chemistry 65.578, for which additional credit is precluded.
Prerequisite: Biochemistry 63.310 or permission of the Institute.
Lectures three hours a week.

Biochemistry 63.491*
Selected Topics in Biochemistry
Selected topics of current interest in biochemistry are offered upon approval by the Director in consultation with members of the Institute.

Biochemistry 63.497
Honours Essay and Research Proposal
An independent research study using library resources. The candidate will prepare a critical review of a topic approved by a faculty advisor. Evaluation will be based on a report and an oral defence of the report.
Precludes additional credit for Biochemistry 63.498.
Prerequisite: Fourth-year standing in an Honours Biochemistry program and permission of the Institute.

Biochemistry 63.498
Research Project
Students carry out a research project approved by the Director, under the supervision of a faculty member of the Institute, in either the Biology or Chemistry departments. A report must be submitted to the supervisor by the last day of classes, and will be examined by committee.
Precludes additional credit for Biochemistry 63.497.
Prerequisites: Biochemistry 63.305* and 63.310 or equivalent, and eligibility to continue in Honours Biochemistry or in Biochemistry and Biotechnology.
Lectures and associated work average at least eight hours a week.

Biochemistry 63.499*
Co-operative Work Term Report 3
This course provides practical experience for students enrolled in the co-operative option. To receive course credit, students must receive a satisfactory evaluation from their work term employer; and present a written report describing their work term project. Graded Sat/Uns.
Prerequisites: Registration in the Biochemistry co-operative option and permission of the Institute.
Four month work term.

Carleton University
2001-2002 Undergraduate Calendar
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